Publications

Publications Citing NIH T32 Training Grant Support:

Leong, B.J. and Last, R.L. Promiscuity, impersonation and accommodation: evolution of plant specialized metabolism. Curr. Opin. Struct. Biol., Volume 47, December 2017, Pages 105–112 https://doi.org/10.1016/j.sbi.2017.07.005.

Wrenbeck E.E., Azouz L.R., Whitehead T.A. (2017), Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded, Nature Comm. 8, Article number: 15695. doi:10.1038/ncomms15695

Moghe, G.D., Leong, B.J., Hurney, S. Jones, A.D. and Last, R.L. 2017. Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant defense related specialized metabolic pathway. eLife 2017;6:e28468 DOI: 10.7554/eLife.28468.

Clark, T.J., Friel, C.A., Grman, E., Shachar-Hill, Y. and Friesen, M.L. (2017) Modelling nutritional mutualisms: challenges and opportunities for data integration. Ecol. Letts. doi: 10.1111/ele.12810

Wrenbeck E. E., Faber, M. S., Whitehead, T. A. (2017). Deep sequencing methods for protein engineering and design. Curr Opin Struct Biol, 45:36-44, doi: 10.1016/j.sbi.2016.11.001

Medina-Cucurella A and Whitehead, TA (2017) Characterizing Protein-Protein Interactions Using Deep Sequencing Coupled to Yeast Surface Display, Methods in Molecular Biology in press

Klesmith, J.R., Bacik, J.P., Wrenbeck, E.E., Michalczyk, R., Whitehead, T.A. (2017). Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning. Proc Natl Acad Sci U S A, 114:2265-2270, doi: 10.1073/pnas.1614437114

Wrenbeck, E.E., Klesmith, J.R., Stapleton, J.A., Adeniran, A., Tyo, K.E.J. and Whitehead T.A. (2016). Plasmid-based one-pot saturation mutagenesis. Nature Methods, 13:928–930. doi:10.1038/nmeth.4029.

Yang, Y., Zienkiewicz, A., Lavell, A. and Benning, C. (2017). Coevolution of Domain Interactions in the Chloroplast TGD1, 2, 3 Lipid Transfer Complex Specific to Brassicaceae and Poaceae Plants. Plant Cell, 29:1500–1515. DOI: https://doi.org/10.1105/tpc.17.00182

Ning, J., Moghe, G., Leong, B.J., Kim, J., Ofner, I., Wang, Z., Adams, C., Jones, A., Zamir, D., Last, RL. (2015).  A feedback insensitive isopropylmalate synthase affects acylsugar composition in cultivated and wild tomato. 169:1821-1835. doi:10.1104/pp.15.00474

Tsai, C.H., Warakanont, J., Takeuchi, T., Sears, B.B., Moellering, E.R., Benning, C. (2014). The protein Compromised Hydrolysis of Triacylglycerols 7 (CHT7) acts as a repressor of cellular quiescence in Chlamydomonas. Proc. Natl. Acad. Sci. U.S.A. 111:15833–15838. doi:/10.1073/pnas.1414567111.

 

Other Publications from our Trainees:

Malmstrom, C.M., Bigelow, P., Trebicki, P., Busch, A.K., Friel, C., Cole, E., Abdel-Azim, H., Phillippo, C. and Alexander, H.M. 2017. Virus Res. doi.org/10.1016/j.virusres.2017.07.006

Clark. T. J., & Lu. Y. (2015). Analysis of loss-of-function mutants in aspartate kinase and homoserine dehydrogenase genes points to complexity in the regulation of aspartate-derived amino acid contents. Plant Physiol. 168:15121526.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528744/.

Lantz. A.T., Cardiello. J., Gee. T., Richards. M.,Rosenstiel. T., Fisher. A. (2015). Biochemical characterization of an isoprene synthase from Campylopus introflexus (heath star moss).  Plant Physiology and Biochemistry. 94:209-215. doi: 10.1016/j.plaphy.2015.06.008

Brasher, M., Surmacz, L., Leong, B., Pitcher, J., Swiezewska, E., Pichersky, E., Akhtar, T.A. (2015).  A two-component enzyme complex is required for doichol biosynthesis in tomato.  Plant J. 82:903-14. doi: 10.1111/tpj.12859

Thireault, C., Shyu, C., Yoshida, Y., St Aubin, B., Campos, M.L. and Howe, G.A. (2015). Repression of jasmonate signaling by a non-TIFY JAZ protein in Arabidopsis. Plant J, 82:669-79 doi: 10.1111/tpj.12841, 25846245

Bienick, M., Young, K., Klesmith, J., Detwiler, E.E., Tomek K., Whitehead T. (2014). The Interrelationship between Promoter Strength, Gene Expression, and Growth Rate. PLOSOne 9(10): e109105. DOI: 10.1371/journal.pone.0109105.